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Breaking barriers through innovation

With PharmFilm® and AdrenaVerse™ we are helping patients overcome treatment barriers, revolutionizing drug delivery, and diversifying our pipeline.

Our core technologies

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PharmFilm:
The proven oral film platform

Aquestive was founded over 20 years ago on the promise of PharmFilm, our patented drug delivery method that enables precise oral delivery of almost any active pharmaceutical ingredient (API). PharmFilm isn’t just the technology behind two of our pipeline candidates—it’s also utilized by our strategic licensees who commercialize millions of doses of PharmFilm every year.

Learn more about PharmFilm
AdrenaVerse logo
AdrenaVerse:
Transforming epinephrine delivery

Aquestive's new AdrenaVerse prodrug platform is a breakthrough technology that allows precise control of epinephrine absorption and release across mucosal surfaces and skin. By converting inactive epinephrine into its active form at the site of inflammation, AdrenaVerse enables targeted treatment with sustained duration, minimal side effects, and broad potential across allergic and dermatologic indications.

Learn more about AdrenaVerse
Pharmfilm single strip
WHAT IS PHARMFILM?

Pharmfilm Logo

PharmFilm® is a unique and versatile technology for high-performance drug delivery. A small, postage-stamp sized film is taken orally, allowing for fast absorption of the active ingredient without the need for water or liquids. All routes of administration allow for direct entry into the bloodstream, without needles, pills, or injections. PharmFilm strips are packaged in child-proof foil pouches, which are resistant to water, extremely durable, and allow for on-the-go convenience.

1
Sublingual administration
Dissolves quickly for rapid uptake and onset of action
Sublingual administration
2
Buccal administration
Greater surface area and reduced salivation
Buccal administration
3
Lingual administration
Rapid disintegration, and controlled release
Lingual administration

PharmFilm customization 
for licensees

Every medicine is different, so Aquestive follows a drug-by-drug approach for harnessing film technology to achieve target product profiles and clinical improvement goals. Our Formulation Engineering team optimizes absorption using proprietary matrices, pH modifiers, and FDA-approved permeation enhancers to meet target product profiles.
Adaptable polymer matrix
Variety of flavors
Array of FDA-approved
permeation enhancers
Range of drug loads

With three routes of administration (buccal, sublingual, and lingual), PharmFilm offers unmatched flexibility for licensees looking to differentiate their product and offer patients easy, convenient dosing.

Contact the Aquestive business development team
AdrenaVerse logo
WHAT IS ADRENAVERSE?

AdrenaVerse: 
the next generation of epinephrine therapy

The AdrenaVerse platform contains a library of over 20 epinephrine prodrugs that demonstrate control of absorption and conversion rates across a variety of dosage forms including lotions, creams, and ointments (LCOs) and delivery sites. We believe the AdrenaVerse technology has the potential to revolutionize treatment options for patients facing allergies and dermatological conditions.
ADRENAVERSE IN DETAIL

AdrenaVerse is a proprietary prodrug platform that enables local epinephrine exposure without undesirable systemic exposure.

Localized activity
Multiple formation options, including gels and creams
Broad potential across inflammatory and autoimmune conditions
Use of existing Aquestive manufacturing infrastructure
Patent protection through 2046

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Our leaders and values

Meet the people who lead Aquestive Therapeutics.

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Clinical trial data

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Explore Our Pipeline

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